Publications

論文

最新の論文

査読付き論文

CRISPR-Cas3-based editing for targeted deletions in a mouse model of transthyretin amyloidosis

  • Saeko Ishida, Yusuke Sato, Keisuke Chosa, Eri Ezawa, Yuko Yamauchi, Masaaki Oyama, Hiroko Kozuka-Hata, Rina Ito, Rikako Sato, Masatoshi Maeki, Tomo-o Ishikawa, Kenichi Yamamura, Kohei Takeshita, Kensuke Yamaguchi, Yuta Kochi, Fumitaka Hashiya, Yiwei Liu, Naoko Abe, Hiroshi Abe, Yoshiki Sekijima, Kazuto Yoshimi, Tomoji Mashimo
  • Nat Biotechnol (2026)
    https://doi.org/10.1038/s41587-025-02949-6

The effect of guide RNA thermal denaturation on the quality of Cas9 ribonucleoprotein-loaded lipid nanoparticle formulations

  • Rina Shimizu, Yuji Kashiwakura, Morisada Hayakawa, Shunsuke Kita, Mina Sato, Masatoshi Maeki, Manabu Tokeshi, Katsumi Maenaka, Tsukasa Ohmori, Yuma Yamada, Hideyoshi Harashima, Yusuke Sato
  • RSC Pharm., 3, 77-87 (2026)
    https://doi.org/10.1039/D5PM00189G

Programmable Antigen-Specific Immunity via Self-Adjuvanting Nanovaccines Co-Delivering Immune Modulators

  • Keita Ito, Yoshiyuki Manabe, Shino Ohshima, Masatoshi Maeki, Manabu Tokeshi, Hiroshi Inaba, Kazunori Matsuura, Kazuya Kabayama, Yoshie Kametani, Koichi Fukase
  • Angew. Chem. Int. Ed., e20474 (2025)
    https://doi.org/10.1002/anie.202520474

Noncompetitive Fluorescence Polarization Aptamer Assay for Detecting SARS-CoV-2 Variants

  • Chang Yu-Ting, Rigel Suzuki, Yoichiro Fujioka, Akihiko Ishida, Ayuko Imai, Mao Fukuyama, Motohiro Kasuya, Yusuke Ohba, Takasuke Fukuhara, Koji Shigemura, Akihide Hibara, Masatoshi Maeki, Manabu Tokeshi
  • ACS Omega, 10, 51228–51235 (2025)
    https://doi.org/10.1021/acsomega.5c06304

Examining the Impact of Storage Conditions on the Stability of a Liquid Formulation of mRNA-Loaded Lipid Nanoparticles

  • Mina Sato, Eleni Samaridou, Moritz Beck-Broichsitter, Masatoshi Maeki, Shunsuke Kita, Manabu Tokeshi, Katsumi Maenaka, Hideyoshi Harashima, Yusuke Sato
  • Pharmaceutics, 17, 1194 (2025)
    https://doi.org/10.3390/pharmaceutics17091194

その他

特集連動◎新時代に入った送達技術：北海道大の真栄城氏、マイクロ流路を用いてLNPを大量製造するGMP装置を実用化へ

  • 真栄城正寿
  • 日経バイオテク

テクノロジーの最新動向からニッポンの未来を読み解く2024-2030 大予測

  • 真栄城正寿
  • 日経トレンディ2024年1月号