Publications

論文

2023

査読付き論文

Controlling Lamellarity and Physicochemical Properties of Liposomes Prepared Using a Microfluidic Device

Yuka Matsuura-Sawada, Shuya Uno, Masatoshi Maeki, Koichi Wada, Manabu Tokeshi
Biomaterials Science,
The article was first published on 01 Feb 2023
Biomater. Sci., 2023,11, 2419-2426
https://doi.org/10.1039/D2BM01703B

A System that Delivers an Antioxidant to Mitochondria for the Treatment of Drug-Induced Liver Injury

Mitsue Hibino, Masatoshi Maeki, Manabu Tokeshi, Yoichi Ishiｔｓuka, Hideyoshi Harashima, Yuma Yamada
Scientific Reports volume 13, Article number: 6961 (2023)
doi: 10.1038/s41598-023-33893-7.

Mass production system for RNA-loaded lipid nanoparticles using piling up microfluidic devices

M. Maeki, Y. Okada, S. Uno, K. Sugiura, Y. Suzuki, K. Okuda, Y. Sato, M. Ando, H. Yamazaki, M. Takeuchi, A. Ishida, H. Tani, H. Harashima, M. Tokeshi,
Applied materials today,Volume 31, April 2023, 101754

Antigen/Adjuvant-Displaying Enveloped Viral Replica as a Self-Adjuvanting Anti-Breast-Cancer Vaccine Candidate

Keita Ito, Hiroto Furukawa, Hiroshi Inaba, Shino Oshima, Yoshie Kametani, Masatoshi Maeki, Manabu Tokeshi, Xuhao Huang, Kazuya Kabayama, Yoshiyuki Manabu, Koichi Fukase, Kazunori Matsuura
J. Am. Chem. Soc. 2023, 145, 29, 15838–15847 Published inissue 26 July 2023

Construction of the Systemic Anticancer Immune Environment in Tumor-Bearign Humanized Mouse by Uisng Liposome-Encapsulated Anti-Programmed Death Ligand 1 Antibody-Conjugated Progesterone

Yoshie Kametani, Ryoji Ito, Shino Ohshima, Yoshiyuki Manabe, Yusuke Ohno, Tomoka Shimizu, Soga Yamada, Nagi Katano, Daiki Kirigaya, Keita Ito, Takuya Matsumoto, Banri Tsuda, Hirofumi Kashiwagi, Yumiko Goto, Atsushi Yasuda, Masatoshi Maeki, Manabu Tokeshi, Toshiro Seki, Koichi Fukase, Mikio Mikami, Kiyoshi Ando, Hitoshi Ishimoto, Takashi Shiina
Front. Immunol., 10 July 2023 Sec. Cancer Immunity and Immunotherapy Volume 14 - 2023

A Portable Liquid Chromatography System Based on a Separation/Detection Chip Module Consisting of a Replaceable Ultraviolet-Visible Absorbance or Contactless Conductivity Detection Unit

Akihiko Ishida, Takuma Nishimura, Kaito Koyama, Masatoshi Maeki, Hirofumi Tani, Manabu Tokeshi
Journal of Chromatography A, Volume 1706, 13 September 2023, 464272

Structure of Lasso Peptide Epimerase MsIH Reveals Metal-Dependent Acid/Base Catalytic Mechanism

Yu Nakashima, Atsushi Kawakami, Yasushi Ogasawara, Masatoshi Maeki, Manabu Tokeshi, Tohru Dairi, Hiroyuki Morita
Nature Communications, 14, 4752 (2023).

Micro- and Nanochamber Array System for Single Enzyme Assays

Kazuki Iijima, Noritada Kaji, Manabu Tokeshi, Yoshinobu Baba
Scientific Reports, 13, 13322 (2023).

An Ionizable Lipid Material with a Vitamin E Scaffold as an mRNA Vaccine Platform for Efficient Cytotoxic T Cell Responses

Ryotaro Oyama, Harumichi Ishigame, Hiroki Tanaka, Naho Tateshita, Moeko Itazawa, Ryosuke Imai, Naomasa Nishiumi, Jun-ichi Kishikawa, Takayuki Kato, Yoshifumi Nishikawa, Jessica Anindita, Masatoshi Maeki, Manabu Tokeshi, Kota Tange, Yuta Naka, Yu Sakurai, Takaharu Okada, Hidetaka Akita
ACS Nano 2023, 17, 19, 18758–18774 Publication Date:September 26, 2023

Rapid Determination of Domoic Acid in Seafood by Fluorescence Polarization Immunoassay Using a Portable Analyzer

Yu Ogura, Mao Fukuyama, Motohiro Kasuya, Koji Shigemura, Sergei A. Eremin, Manabu Tokeshi, Akihide Hibara
Analytical Sciences,2023 Aug 31. doi: 10.1007/s44211-023-00413-6. Online ahead of print.

Development of Polymer-Lipid Hybrid Nanoparticles for Large-Sized Plasmid DNA Transfection

Masatoshi Maeki, Shuya Uno, Kaisei Sugiura, Yusuke Sato, Yoichiro Fujioka, Akihiko Ishida, Yusuke Ohba, Hideyoshi Harashima, Manabu Tokeshi
ACS Appl. Mater. Interfaces 2024, 16, 2, 2110–2119
https://doi.org/10.1021/acsami.3c14714

Understanding the effects of ethanol on the liposome bilayer structure using microfluidic-based time-resolved small-angle X-ray scattering and molecular dynamics simulations

Masatoshi Maeki, Niko Kimura, Yuto Okada, Kazuki Shimizu, Kana Shibata, Yusuke Miyazaki, Akihiko Ishida, Kento Yonezawa, Nobutaka Shimizu, Wataru Shinoda, and Manabu Tokeshi
Nanoscale Adv., 2024, Advance Article
https://doi.org/10.1039/D3NA01073B

総説・解説・著書

液晶素子を利用した小型蛍光偏光装置の開発

渡慶次学, 重村浩治, 火原彰秀
光技術コンタクト, 61, 10-15 (2023).

その他

テクノロジーの最新動向からニッポンの未来を読み解く2024-2030 大予測

真栄城正寿
日経トレンディ2024年1月号

特集連動◎新時代に入った送達技術：北海道大の真栄城氏、マイクロ流路を用いてLNPを大量製造するGMP装置を実用化へ

真栄城正寿
日経バイオテク