Publications

論文

2022

査読付き論文

Dimethoxytriadinylation LC-MS/MS of Novichok A-Series Degradation Products in Human Urine

  • Akinori Yamaguchi, Hajime Miyaguchi, Manabu Tokeshi
  • Analytical Chemistry, Volume 94, Issue 11, 4658–4665(2022)

Production of siRNA-Loaded Lipid Nanoparticles using a Microfluidic Device

  • Masatoshi Maeki, Yuto Okada, Shuya Uno, Ayuka Niwa, Akihiko Ishida, Hirofumi Tani, Manabu Tokeshi
  • Journal of Visualized Experiments , 181 , e62999(2021)

Microfluidic technologies and devices for lipid nanoparticle-based RNA delivery

  • Masatoshi Maeki , Shuya Uno , Ayuka Niwa , Yuto Okada , ManabuTokeshi
  • Journal of Controlled Release , 344 , 80-96(2021)

Microfluidic Device-Enabled Mass Production of Lipid-Based Nanoparticles for Applications in Nanomedicine and Cosmetics

  • Yuka Matsuura-Sawada, Masatoshi Maeki, Takaaki Nishioka, Ayuka Niwa, Jun Yamaguchi, Masashi Mizoguchi, Koichi Wada, Manabu Tokeshi
  • ACS Appl. Nano Mater. 2022, 5, 6, 7867–7876

Non-Competitive Fluorescence Polarization Immunosensing for CD9 detection Using a Peptide as a Tracer

  • Kazuki Takahashi, Shunsuke Chida, Thanawat Suwatthanarak, Mikiko Iida, Min Zhang, Mao Fukuyama, Masatoshi Maeki, Akihiko Ishida, Hirofumi Tani, Takao Yasui, Yoshinobu Baba, Akihide Hibara, Mina Okochi, Manabu Tokeshi
  • Lab Chip, 2022, 22, 2971-2977

On the Size-Regulation of RNA-Loaded Lipid Nanoparticles Synthesized by Microfluidic Device

  • Kento Okuda, Yusuke Sato, Kazuki Iwakawa, Kosuke Sasaki, Nana Okabe, Masatoshi Maeki, Manabu Tokeshi, Hideyoshi Harashima
  • Journal of Controlled Release, August 2022, Pages 648-659

Preparation of Size-Tunable Sub-200 nm PLGA-Based Nanoparticles with a Wide Size Range Using a Microfluidic Device

  • Bao Yi, Masatoshi Maeki, Akihiko Ishida, Hirofumi Tani, Manabu Tokeshi
  • PLOS ONE, 2022; 17(8): e0271050.

Effect of Organic Solvent on a Production of PLGA-Based Drug-Loaded Nanoparticles Using a Microfluidic Device

  • Bao Yi, Masatoshi Maeki, Akihiko Ishida, Hirofumi Tani, Manabu Tokeshi
  • ACS Omega 2022, 7, 37, 33079–33086

Fine-Tuning the Encapsulation of a Photosensitizer in Nanoparticles Reveals the Relationship Betweeen Internal Structure and Phototherapeutic Effects

  • Fumika Kubota, Satrialdi, Yuta Takano, Masatoshi Maeki, Manabu Tokeshi, Hideyoshi Harashima, Yuma Yamada
  • Journal of Biophotonics, 01 September (2022)e202200119
    https://doi.org/10.1002/jbio.202200119

Microfluidic Platform Enabling Efficient On-Device Preparation of Lipid Nanoparticles for Formulation Screening

  • Yuka Matsuura-Sawada, Shuya Uno, Masatoshi Maeki, Koichi Wada, Manabu Tokeshi
  • ACS Applied Engineering Materials,November 10, (2022)278-286
    https://doi.org/10.1021/acsaenm.2c00062

Microfluidic Paper-based Analytical Devices for Cancer Diagnosis

  • Ahmed A. Shalaby, Chia-Wen Tsao, Akihiko Ishida, Masatoshi Maeki, Manabu Tokeshi
  • Sensors and Actuators B, Volume 379, 15 March 2023, 133243

マイクロ流体デバイスを利用した下痢性貝毒オカダ酸の蛍光偏光免疫分析におけるブロッキング剤添加の影響

  • 千田駿亮, 高橋和希, 福山真央, 粕谷素洋, 真栄城正寿, 石田晃彦, 谷博文, 重村幸治, Anatoly V. Zherdev, Sergei A. Eremin, 火原彰秀, 渡慶次学
  • 分析化学, accepted.

総説・解説・著書

マイクロ流体デバイスを用いた脂質ナノ粒子調製

  • 真栄城正寿
  • Drug Delivery System , 37 , 81-83 (2022).

脂質ナノ粒子の粒径制御技術と核酸医薬への応用

  • 杉浦魁星、宇野秀哉、真栄城正寿
  • 月刊ファインケミカル, 51,18-24（2022）

LNPの製造方法・製造プロセス

  • 真栄城正寿、渡慶次学
  • PHARM TECH JAPAN、Vol.39 No.3、ｐ.51-56(2023)